Stadium: Moretz Stadium Round: 1
| NCAAF | 2022/09/30 19:00 | Virginia Wise Highland Cavaliers v Lenoir Rhyne Bears | W | 10-42 |
| NCAAF | 2021/10/02 18:00 | Virginia Wise Highland Cavaliers v Lenoir Rhyne Bears | L | 35-28 |
| NCAAF | 2019/10/05 18:00 | Lenoir Rhyne Bears v Virginia Wise Highland Cavaliers | W | 63-6 |
| NCAAF | 2023/09/23 17:00 | Carson–Newman Eagles v Lenoir Rhyne Bears | W | 7-24 |
| NCAAF | 2023/09/16 22:00 | Lenoir Rhyne Bears v Erskine Flying Fleet | W | 62-0 |
| NCAAF | 2023/09/09 22:00 | Fayetteville State Broncos v Lenoir Rhyne Bears | W | 10-24 |
| NCAAF | 2023/09/02 22:00 | Lenoir Rhyne Bears v St Augustines Falcons | W | 45-7 |
| NCAAF | 2022/11/12 18:00 | Lenoir Rhyne Bears v Tusculum Pioneers | W | 34-14 |
| NCAAF | 2022/11/05 18:00 | Catawba Indians v Lenoir Rhyne Bears | W | 10-62 |
| NCAAF | 2022/10/29 17:00 | Lenoir Rhyne Bears v Wingate Bulldogs | L | 21-24 |
| NCAAF | 2022/10/22 18:00 | Lenoir Rhyne Bears v Newberry Wolves | L | 24-38 |
| NCAAF | 2023/09/23 18:00 | Virginia Wise Highland Cavaliers v Limestone Saints | L | 17-38 |
| NCAAF | 2023/09/16 20:00 | Barton Bulldogs v Virginia Wise Highland Cavaliers | L | 28-24 |
| NCAAF | 2023/09/09 16:00 | Thomas More Saints v Virginia Wise Highland Cavaliers | L | 37-0 |
| NCAAF | 2023/09/02 23:00 | Virginia Wise Highland Cavaliers v Union College Bulldogs | W | 48-0 |
| NCAAF | 2022/11/12 18:30 | Wingate Bulldogs v Virginia Wise Highland Cavaliers | L | 45-7 |
| NCAAF | 2022/11/05 19:00 | Carson–Newman Eagles v Virginia Wise Highland Cavaliers | L | 38-22 |
| NCAAF | 2022/10/29 16:00 | Virginia Wise Highland Cavaliers v Mars Hill Lions | L | 16-20 |
| NCAAF | 2022/10/22 20:00 | Erskine Flying Fleet v Virginia Wise Highland Cavaliers | W | 13-28 |