Stadium: Alumni Memorial Stadium Round: 1
| NCAAF | 2021/11/06 17:00 | Johnson C Smith GB v Livingstone C. BB | W | 3-17 |
| NCAAF | 2021/10/30 18:00 | Fayetteville State Broncos v Livingstone C. BB | L | 34-0 |
| NCAAF | 2021/10/23 17:00 | Winston-Salem State v Livingstone C. BB | L | 21-0 |
| NCAAF | 2021/10/16 17:00 | Livingstone C. BB v Shaw Bears | L | 9-20 |
| NCAAF | 2021/10/09 17:30 | Livingstone C. BB v St Augustines Falcons | W | 21-7 |
| NCAAF | 2021/10/02 18:30 | Elizabeth City State Vikings v Livingstone C. BB | L | 19-13 |
| NCAAF | 2021/09/25 20:00 | Livingstone C. BB v Bowie State Bulldogs | L | 0-49 |
| NCAAF | 2021/09/18 21:00 | Allen Yellow Jackets v Livingstone C. BB | L | 34-32 |
| NCAAF | 2021/11/13 18:00 | Lenoir Rhyne Bears v Catawba Indians | L | 56-3 |
| NCAAF | 2021/11/06 17:00 | Catawba Indians v Virginia Wise Highland Cavaliers | L | 7-30 |
| NCAAF | 2021/10/30 17:00 | Catawba Indians v Tusculum Pioneers | W | 31-28 |
| NCAAF | 2021/10/23 17:00 | Mars Hill Lions v Catawba Indians | L | 31-14 |
| NCAAF | 2021/10/16 21:00 | Newberry Wolves v Catawba Indians | L | 14-7 |
| NCAAF | 2021/10/09 17:00 | Catawba Indians v Carson–Newman Eagles | W | 33-27 |
| NCAAF | 2021/09/18 17:00 | Catawba Indians v Barton Bulldogs | W | 17-10 |
| NCAAF | 2021/09/11 23:00 | Catawba Indians v Winston-Salem State | W | 28-6 |